Advice and information on all aspects of tablet dissolution testing

Basket Handling & Storage

One of the most common problems with dissolution baskets is that they can easily become bent. Poor handling can cause this – the basket mesh is easily bent and good practice dictates that a basket should only be handled by the rim, not least because oily deposits from fingers can be left on the mesh. This is not always easy and so care is needed.

A bent basket can cause excessive wobble. Basket wobble is measured using a wobble meter on the bottom rim of the basket when affixed to the shaft.

Baskets should be stored correctly to extend their life, they can frequently be found rolling around in a lab drawer. Baskets can easily be stored in the suppliers case or using a specially designed basket holder.

Care should also be exercised to ensure that they are clean prior to use. Often the dosage form can clog the mesh which will prevent free media movement into the basket. Careful cleaning is required to ensure there is no contamination between tests.